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Последни новини, научни статии и полезна информация за молекулярната онкологична диагностика и персонализираната терапия.
Patritumab deruxtecan in breast cancer treatment: a drug evaluation
Breast cancer is a complex disease due to its heterogeneity. While there have been impressive advancements in the treatment of the different breast cancer subty...
Inactivation of stress pathway allows ER+ breast cancer cells to evade treatment
A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stres...
Proteoform medicine: characterizing and targeting protein forms in human disease
Proteoforms are the diverse protein molecules produced from a single gene whose primary sequence and composition can be diversified by genetic, transcriptomic, translational and post-translational variation. This Review synthesizes technologies and network ap…
Opportunities and challenges of targeting cGAS–STING in cancer
In this Review, Lu et al. discuss the dual role of the cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS)–stimulator of interferon genes (STING) pathway in cancer, emphasizing its involvement in both tumour suppression and promotion. …
Woman's Lung Cancer Misdiagnosed as Pneumonia, Allergies, Stress
At just 42, a mom of three kids was diagnosed with stage 4 lung cancer, which had already spread to her brains and bones. Doctors thought she had pneumonia.
HUTCHMED Highlights Publication of Phase III SACHI Results in The Lancet
— First randomized Phase III trial confirming the efficacy of MET inhibition in patients with advanced NSCLC and acquired MET amplification after progression on prior EGFR-TKI treatment —
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