Биомаркери
Статии в категория "Биомаркери" - 29 публикации
Optineurin binding to the novel interacting partner Junction plakoglobin prevents muscle atrophy in mice
Skeletal muscle atrophy is a debilitating condition that accompanies a number of diseases, but there are few known therapeutic targets to reverse it. This study identifies Optineurin as a regulator of muscle homeostasis, showing that it binds to JUP and activ…
Inside AstraZeneca’s long-term strategy in lung cancer
Decades-long research has yielded a strong and growing franchise built around drugs for a genetic form of lung cancer.
Identification of Targetable EGFR Mutations in Ovarian Cancer
Ovarian cancer driven by an oncogenic <i>EGFR</i> mutation is a rare occurrence, yet it is an actionable molecular target with EGFR-directed inhibitors. This un...
Beyond the Scalpel: EGFR Mutation Predicts Intraoperative Blood Loss and Transfusion Needs During Lung Cancer-derived Spinal Metastasis Surgery
This study identified EGFR mutation as a novel molecular predictor of hemorrhagic risk in LCSM surgery, independent of systemic therapy status. The quantifiable...
Нови възможности за BRCA тестване
BRCA1 и BRCA2 мутациите са свързани с повишен риск от рак на гърдата и яйчниците. Научете за най-новите методи за тяхното откриване.
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