Биомаркери

Статии в категория "Биомаркери" - 29 публикации

Palbociclib improves progression-free survival in HER2 positive breast cancer
Биомаркери

Palbociclib improves progression-free survival in HER2 positive breast cancer

PrECOG, LLC, today announced the publication of final results from the pivotal phase 3 PATINA study in the New England Journal of Medicine (NEJM).

4 февруари 2026 г.2 мин
Proteoform medicine: characterizing and targeting protein forms in human disease
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Proteoform medicine: characterizing and targeting protein forms in human disease

Proteoforms are the diverse protein molecules produced from a single gene whose primary sequence and composition can be diversified by genetic, transcriptomic, translational and post-translational variation. This Review synthesizes technologies and network ap…

4 февруари 2026 г.2 мин
Opportunities and challenges of targeting cGAS–STING in cancer
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Opportunities and challenges of targeting cGAS–STING in cancer

In this Review, Lu et al. discuss the dual role of the cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS)–stimulator of interferon genes (STING) pathway in cancer, emphasizing its involvement in both tumour suppression and promotion. …

4 февруари 2026 г.2 мин
Woman's Lung Cancer Misdiagnosed as Pneumonia, Allergies, Stress
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Woman's Lung Cancer Misdiagnosed as Pneumonia, Allergies, Stress

At just 42, a mom of three kids was diagnosed with stage 4 lung cancer, which had already spread to her brains and bones. Doctors thought she had pneumonia.

4 февруари 2026 г.7 мин
HUTCHMED Highlights Publication of Phase III SACHI Results in The Lancet
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HUTCHMED Highlights Publication of Phase III SACHI Results in The Lancet

— First randomized Phase III trial confirming the efficacy of MET inhibition in patients with advanced NSCLC and acquired MET amplification after progression on prior EGFR-TKI treatment —

4 февруари 2026 г.11 мин
The polygenic, omnigenic and stratagenic models of complex disease risk
Биомаркери

The polygenic, omnigenic and stratagenic models of complex disease risk

This study discusses polygenic, omnigenic and stratagenic models developed to explain multigenic disease risk. It proposes means to test their validity, which has implications for research, drug development and precision medicine.

4 февруари 2026 г.2 мин

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